HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Adamantylthiourea → HCID 21459009, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Adamantylthiourea | HCID 796429 | — |
| Reactant | 2-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone | HCID 21845596 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 21459009 | HCID 21459009 | — |
Reaction Steps
A suspension of 8.3 g of 2-bromo-3',4'-dihydroxy-5'-nitroacetophenone is treated with 1-(1-adamantyl)-2-thiourea in 90 ml of n-butanol and the mixture is heated to boiling under reflux for 4 hours. After cooling to room temperature, the crystals are filtered under suction and recrystallized from n-butanol. There is obtained 5-[2-(1-adamantylamino)-5-thiazolyl]-3-nitropyrocatechol hydrobromide of m.p. 245°-247°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05236952 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-4418d6d7b46746acabc735b9b8d39597 |
| Source note | uspto-grants-1993_08 |