HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malonic Acid → 3-(2-Bromo-5-nitrophenyl)prop-2-enoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malonic Acid | HCID 867 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 2-Bromo-5-nitrobenzaldehyde | HCID 11138942 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 3-(2-Bromo-5-nitrophenyl)prop-2-enoic acid | HCID 54106243 | 57% |
Reaction Steps
This reaction was carried out similarly to Example 1, with 2-bromo-5-nitrobenzaldehyde and malonic acid in pyridine and with piperidine. The product of melting point 185° C, was obtained in 57% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05237089 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-15a25f359fbd49eba28b49004fd031d8 |
| Source note | uspto-grants-1993_08 |