Chlorine → N'-tert-butylbenzohydrazide

HRID 2254920Notes

Reaction equation

HRID 2254920 reaction equation
ClCl.[C:3]([NH:7][NH:8][C:9](=[O:17])[C:10]1[CH:15]=[CH:14][CH:13]=[C:12](Cl)[CH:11]=1)([CH3:6])([CH3:5])[CH3:4].C(NNC(=O)C1C=CC(C#N)=CC=1)(C)(C)C.C(NNC(=O)C1C(=CC=CC=1)N)(C)(C)C.[H][H]>>[C:3]([NH:7][NH:8][C:9](=[O:17])[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)([CH3:6])([CH3:4])[CH3:5]

Participants

6

Reactant 5

HCID 24526ChlorineHCID 2797474HCID 2797474, compoundHCID 15617772HCID 15617772, compoundHCID 15617773HCID 15617773, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 299436N'-tert-butylbenzohydrazide

Procedure

The above reactions are illustrated below: ##STR15## wherein Q is halogen, preferably chlorine; R is tert-butyl or tert-amyl. Other compounds that can be prepared by the above procedure using the appropriately substituted benzoyl halide include: m-chlorobenzoic acid, 2-tert-butylhydrazide, mp 120°-123° C.; p-cyanobenzoic acid, 2-tert-butylhydrazide, mp 135°-136° C.; anthranilic acid, 2-tert-butylhydrazide, mp 165°-167° C.; tert-butyl or isopropyl; and X is hydrogen, halogen, C1 -C3 alkyl, methoxy, methylamino, NH2, nitro or CF3.

Workup

  1. customOther compounds that can be prepared by the above procedure

Sources & evidence

ORD record
ord-9be9a6f759644e5e97ac27d7e5a81dbb
Source dataset
uspto-grants-1993_08
Patent number
US05237099

Reaction notes

Loading…