Water → HCID 14084861, compound

Participants

Reaction Steps

19.5 g (90 mmol) of said product (14-1) was dissolved in 200 ml of ethanol, and the solution was added with 1.7 g (45 mmol) of sodium borohydride and stirred at room temperature for 2 hours. The reaction mixture was poured into water and extracted with ethyl acetate, and the resultantly formed organic layer was washed with water and brine successively, then dried over anhydrous magnesium sulfate and concentrated under reduced pressure to obtain 19.1 g of 5-phenyl-1,1,1-trifluoro-2-pentanol (15-1) as a colorless liquid. Yield: 97%.

Provenance & Evidence