Zinc Acetate → HCID 107684, compound

HRID 2255036Notes

Reaction equation

HRID 2255036 reaction equation
[OH-].[Na+].[CH:3]1[N:7]=[CH:6][NH:5][C:4]=1[CH2:8][C@H:9]([NH:13][C:14]([CH2:16][CH2:17][NH2:18])=[O:15])[C:10]([OH:12])=[O:11].C([O-])(=O)C.[Zn+2:23].C([O-])(=O)C>CO>[CH:3]1[N:7]=[CH:6][NH:5][C:4]=1[CH2:8][CH:9]([N:13]=[C:14]([O-:15])[CH2:16][CH2:17][NH-:18])[C:10]([O-:12])=[O:11].[Zn+2:23]

Participants

5

Reactant 3

HCID 11192Zinc AcetateHCID 14798Sodium HydroxideHCID 439224Carnosine

Product 1

HCID 107684HCID 107684, compoundYield 97.6%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

In 100 ml of methanol, 3.51 g of sodium hydroxide was dissolved, and 9.96 g of L-carnosine was added to obtain a homogeneous solution. To this solution, a solution obtained by dissolving 9.67 g of zinc acetate.2H2O into 145 ml of methanol was dropped over 30 minutes, while the solution was stirred, to gradually produce white precipitate therein. After finishing of the dropping, the solution was stirred for 2 hours and then left it overnight as was. The solution was filtered, and the precipitation was washed by 140 ml of water and then air-dried at 80° C. for 5 hours to obtain 12.4 g of white powdery crystals. The results of an analysis of the obtained material are as follows:

Workup

  1. customto obtain a homogeneous solution
  2. customTo this solution, a solution obtained
  3. stirringthe solution was stirred for 2 hours
  4. filtrationThe solution was filtered
  5. customthe precipitation
  6. washwas washed by 140 ml of water
  7. customair-dried at 80° C. for 5 hours

Sources & evidence

ORD record
ord-27c86fba05634f088ecefa2a19dc0f1a
Source dataset
uspto-grants-1993_08
Patent number
US05238931

Reaction notes

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