HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-(Chloromethyl)-6,7-dimethoxy-3,4-dihydro-1H-2-benzopyran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Chloro-1,1-diethoxyethane | HCID 12128 | — |
| Reactant | 3,4-Dimethoxyphenethyl alcohol | HCID 81911 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(Chloromethyl)-6,7-dimethoxy-3,4-dihydro-1H-2-benzopyran | HCID 12828435 | 88% |
Reaction Steps
A mixture of 3,4-dimethoxybenzeneethanol and 62,8 g of chloroacetaldehyde diethylacetal in 1 l of absolute ethanol saturated with anhydrous hydrochloric acid, was stirred at ambient temperature for 24 h. The solvent was evaporated and 88,4 g (88,8%) of 1-chloromethyl-3,4-dihydro-6,7-dimethoxy-1H-2-benzopyran was obtained by distillation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05238939 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-ac2e9b7b13634166a3f761891cb795ee |
| Source note | uspto-grants-1993_08 |