Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2255142Generated: October 26, 2026

Boron trifluoride etherate → 2,2-Bis(4-fluorophenyl)acetaldehyde

https://huagongshe.com/reaction/2255142

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoron trifluoride etherateHCID 8000—
Reactant2,2-Bis(4-fluorophenyl)oxiraneHCID 13983937—
SolventTolueneHCID 1140—
Product2,2-Bis(4-fluorophenyl)acetaldehydeHCID 12549104—

Reaction Steps

Under vigorous stirring 18,5 g of boron trifluoride etherate was added slowely to a solution of 60,6 g of 2,2-bis(4-fluorophenyl)oxirane in 450 ml of toluene. The mixture was washed twice with water, the solvent was evaporated and the residue was distilled to yield α-(4-fluorophenyl)-4-fluorobenzeneacetaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05238939
Source datasetuspto-grants-1993_08
ORD IDord-c1965b09dcca4c32a74a70caec8f68a3
Source noteuspto-grants-1993_08