Acetic Anhydride → HCID 57114275, compound

HRID 2255211Notes

Reaction equation

HRID 2255211 reaction equation
O1CCOC1[C:6]1[CH:7]=[C:8]([C:15]([OH:17])=[O:16])[C:9]([C:12]([OH:14])=[O:13])=[N:10][CH:11]=1.[C:18]([O:21][C:22](=O)[CH3:23])(=[O:20])C>N1C=CC=CC=1>[O:21]1[CH2:22][CH2:23][O:20][CH:18]1[C:7]1[CH:6]=[CH:11][N:10]=[C:9]([C:12]([OH:14])=[O:13])[C:8]=1[C:15]([OH:17])=[O:16]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 15672407HCID 15672407, compound

Product 1

HCID 57114275HCID 57114275, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A solution of 5-(1,3-dioxolan-2-yl)-2,3-pyridinedicarboxylic acid (2.86 g, 0.012 mol), acetic anhydride (11.3 mL, 0.12 mol) and pyridine is stirred at room temperature for 1 hour and 45 minutes, then at reflux temperature for 4 hours. The reaction mixture is concentrated in vacuo to give the title compound as an oil (2.64 g, 100%), identified by IR spectra analysis.

Workup

  1. temperatureat reflux temperature for 4 hours
  2. concentrationThe reaction mixture is concentrated in vacuo

Sources & evidence

ORD record
ord-843418a98a0f4e349cc8da233939b6a9
Source dataset
uspto-grants-1993_08
Patent number
US05239070

Reaction notes

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