HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 18953963, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 18953969 | HCID 18953969 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 18953963 | HCID 18953963 | 98% |
Reaction Steps
A mixture of 4-(4-chlorophenyl)-2-oxazoleproprionic acid (0.5 g), benzyl bromide (0.25 ml), potassium carbonate (0.33 g) and dimethylformamide (DMF) (10 ml) was stirred for 3 hours at room temperature. The reaction mixture was poured into water to obtain crystals of benzyl 4-(4-chlorophenyl)-2-oxazolepropionate (0.664 g, 98%). Recrystallization from ether-hexane gave colorless prism crystals of mp 66°-67° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05239080 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-dc285f5fc9d241319fe9fe9127b4fad2 |
| Source note | uspto-grants-1993_08 |