HCID 10353234, compound → HCID 10340469, compound

HRID 2255299Notes

Reaction equation

HRID 2255299 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH3:17][N:18]1[C:26]2[C:21](=[CH:22][C:23](/[C:27](/[CH3:32])=[CH:28]/[C:29](O)=[O:30])=[CH:24][CH:25]=2)[CH:20]=[CH:19]1>>[CH3:17][N:18]1[C:26]2[C:21](=[CH:22][C:23](/[C:27](/[CH3:32])=[CH:28]/[C:29]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:30])=[CH:24][CH:25]=2)[CH:20]=[CH:19]1

Participants

3

Reactant 2

HCID 10353234HCID 10353234, compoundHCID 11816929Ethyl 4-(2-aminophenoxy)butanoate

Product 1

HCID 10340469HCID 10340469, compound

Procedure

0.46 g of compound 3 was obtained in a similar manner to those described in the Example 1 and 2 using 2.16 g of ethyl 4-(2-aminophenoxy)butyrate and 1.04 g of 3-(1-methylindol-5-yl)isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-26c9d1e04ed64dfba7bffa3a2b58f1bb
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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