HCID 10083140, compound → HCID 10319965, compound

HRID 2255300Notes

Reaction equation

HRID 2255300 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH2:17]([N:20]1[C:28]2[C:23](=[CH:24][C:25](/[C:29](/[CH3:34])=[CH:30]/[C:31](O)=[O:32])=[CH:26][CH:27]=2)[CH:22]=[CH:21]1)[CH2:18][CH3:19]>>[CH2:17]([N:20]1[C:28]2[C:23](=[CH:24][C:25](/[C:29](/[CH3:34])=[CH:30]/[C:31]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:32])=[CH:26][CH:27]=2)[CH:22]=[CH:21]1)[CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 10083140HCID 10083140, compoundHCID 11816929Ethyl 4-(2-aminophenoxy)butanoate

Product 1

HCID 10319965HCID 10319965, compound

Procedure

177 mg of compound 4 was obtained in a similar manner to those described in the Example 1 and 2 using 481 mg of ethyl 4-(2-aminophenoxy)butyrate and 262 mg of 3-(1-propylindol-5-yl)isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-1ec0a3dfcc254009874ff81fe1feb062
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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