HCID 9971193, compound → HCID 10389623, compound

HRID 2255301Notes

Reaction equation

HRID 2255301 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH2:17]([N:23]1[C:31]2[C:26](=[CH:27][C:28](/[C:32](/[CH3:37])=[CH:33]/[C:34](O)=[O:35])=[CH:29][CH:30]=2)[CH:25]=[CH:24]1)[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]>>[CH2:17]([N:23]1[C:31]2[C:26](=[CH:27][C:28](/[C:32](/[CH3:37])=[CH:33]/[C:34]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:35])=[CH:29][CH:30]=2)[CH:25]=[CH:24]1)[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]

Participants

3

Reactant 2

HCID 9971193HCID 9971193, compoundHCID 11816929Ethyl 4-(2-aminophenoxy)butanoate

Product 1

HCID 10389623HCID 10389623, compound

Procedure

108 mg of compound 7 was obtained in a similar manner to those described in the Examples 1 and 2 using 580 mg of ethyl 4-(2-aminophenoxy)butyrate and 366 mg of 3-(1-hexylindol-5-yl)isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-68470d44ebbb416db1c8873e2f67c65b
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

Loading…