HCID 10334922, compound → HCID 10050683, compound
Reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH2:17]([N:24]1[C:32]2[C:27](=[CH:28][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35](O)=[O:36])=[CH:30][CH:31]=2)[CH:26]=[CH:25]1)[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]>>[CH2:17]([N:24]1[C:32]2[C:27](=[CH:28][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:36])=[CH:30][CH:31]=2)[CH:26]=[CH:25]1)[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]Participants
3
Procedure
217 mg of compound 8 was obtained in a similar manner to those described in the Examples 1 and 2 using 701 mg of ethyl 4-(2-aminophenoxy)butyrate and 470 mg of 3-(1-heptylindol-5 -yl)isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.
Workup
- customobtained
Sources & evidence
- ORD record
- ord-99e22b7611464f3e98a7c1c282458976
- Source dataset
- uspto-grants-1993_08
- Patent number
- US05239083
Reaction notes
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