Ethyl 4-(2-aminophenoxy)butanoate → HCID 19742038, compound

HRID 2255307Notes

Reaction equation

HRID 2255307 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH3:17][CH:18]([CH2:35][CH2:36][CH3:37])[CH2:19][N:20]1[C:28]2[C:23](=[CH:24][C:25](/[C:29](/[CH3:34])=[CH:30]/[C:31](O)=[O:32])=[CH:26][CH:27]=2)[CH:22]=[CH:21]1>>[CH3:17][CH:18]([CH2:35][CH2:36][CH3:37])[CH2:19][N:20]1[C:28]2[C:23](=[CH:24][C:25](/[C:29](/[CH3:34])=[CH:30]/[C:31]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:32])=[CH:26][CH:27]=2)[CH:22]=[CH:21]1

Participants

3

Reactant 2

HCID 11816929Ethyl 4-(2-aminophenoxy)butanoateHCID 19742042HCID 19742042, compound

Product 1

HCID 19742038HCID 19742038, compound

Procedure

0.56 g of compound 14 was obtained in a similar manner to those described in the Examples 1 and 2 using 1.56 g of ethyl 4-(2-aminophenoxy)butyrate and 1.0 g of 3-[1-(2-methylpentyl)indol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-f4b237e4f51a40d1b93d3bc48a56c6e6
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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