HCID 10108783, compound → HCID 11754754, compound
Reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH2:17]([CH:19]([N:24]1[C:32]2[C:27](=[CH:28][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35](O)=[O:36])=[CH:30][CH:31]=2)[CH:26]=[CH:25]1)[CH2:20][CH2:21][CH2:22][CH3:23])[CH3:18]>>[CH2:17]([CH:19]([N:24]1[C:32]2[C:27](=[CH:28][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:36])=[CH:30][CH:31]=2)[CH:26]=[CH:25]1)[CH2:20][CH2:21][CH2:22][CH3:23])[CH3:18]Participants
3
Procedure
1.11 g of compound 18 was obtained in a similar manner to those described in the Examples 1 and 2 using 2.18 g of ethyl 4-(2-aminophenoxy)butyrate and 1.47 g of 3-[1-(1-ethylpentyl)indol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.
Workup
- customobtained
Sources & evidence
- ORD record
- ord-3f02ba420a414f58b026509263323502
- Source dataset
- uspto-grants-1993_08
- Patent number
- US05239083
Reaction notes
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