Ethyl 4-(2-aminophenoxy)butanoate → HCID 19742048, compound

HRID 2255311Notes

Reaction equation

HRID 2255311 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH3:17][CH:18]([CH:20]([C:24]1[NH:25][C:26]2[C:31]([CH:32]=1)=[CH:30][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35](O)=[O:36])=[CH:28][CH:27]=2)[CH2:21][CH2:22][CH3:23])[CH3:19]>>[CH3:17][CH:18]([CH:20]([C:24]1[NH:25][C:26]2[C:31]([CH:32]=1)=[CH:30][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35]([NH:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:36])=[CH:28][CH:27]=2)[CH2:21][CH2:22][CH3:23])[CH3:19]

Participants

3

Reactant 2

HCID 11816929Ethyl 4-(2-aminophenoxy)butanoateHCID 67754373HCID 67754373, compound

Product 1

HCID 19742048HCID 19742048, compound

Procedure

0.93 g of compound 21 was obtained in a similar manner to those described in the Examples 1 and 2 using 2.20 g of ethyl 4-(2-aminophenoxy)butyrate and 1.50 g of 3-[1-(1-methylethyl)butylindol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-758b613adfe141dbb10d39f973f62a23
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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