Ethyl 4-(2-aminophenoxy)butanoate → HCID 19741969, compound

HRID 2255312Notes

Reaction equation

HRID 2255312 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH3:17][CH:18]([N:24]1[C:32]2[C:27](=[CH:28][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35](O)=[O:36])=[CH:30][CH:31]=2)[CH:26]=[CH:25]1)[CH:19]([CH3:23])[CH2:20][CH2:21][CH3:22]>>[CH3:17][CH:18]([N:24]1[C:32]2[C:27](=[CH:28][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:36])=[CH:30][CH:31]=2)[CH:26]=[CH:25]1)[CH:19]([CH3:23])[CH2:20][CH2:21][CH3:22]

Participants

3

Reactant 2

HCID 11816929Ethyl 4-(2-aminophenoxy)butanoateHCID 19741970HCID 19741970, compound

Product 1

HCID 19741969HCID 19741969, compound

Procedure

0.45 g of compound 22 was obtained in a similar manner to those described in the Examples 1 and 2 using 0.75 g of ethyl 4-(2-aminophenoxy)butyrate and 0.50 g of 3-[1-(1,2-dimethylpentyl)indol-5-yl]isocrotonic acid obtained according the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-8f5292ec656e4c04a5be5c22e2ec1710
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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