HCID 10086429, compound → HCID 10367990, compound

HRID 2255318Notes

Reaction equation

HRID 2255318 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH3:17][C:18]1[CH:39]=[CH:38][CH:37]=[CH:36][C:19]=1[CH2:20][N:21]1[C:29]2[C:24](=[CH:25][C:26](/[C:30](/[CH3:35])=[CH:31]/[C:32](O)=[O:33])=[CH:27][CH:28]=2)[CH:23]=[CH:22]1>>[CH3:17][C:18]1[CH:39]=[CH:38][CH:37]=[CH:36][C:19]=1[CH2:20][N:21]1[C:29]2[C:24](=[CH:25][C:26](/[C:30](/[CH3:35])=[CH:31]/[C:32]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:33])=[CH:27][CH:28]=2)[CH:23]=[CH:22]1

Participants

3

Reactant 2

HCID 10086429HCID 10086429, compoundHCID 11816929Ethyl 4-(2-aminophenoxy)butanoate

Product 1

HCID 10367990HCID 10367990, compound

Procedure

291 mg of compound 31 was obtained in a similar manner to those described in the Examples 1 and 2 using 521 mg of ethyl 4-(2-aminophenoxy)butyrate and 517 mg of 3-[1-(2-methylbenzyl)indol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-0b1b78d2f0db47389dd878d96d503d10
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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