HCID 10402839, compound → HCID 10480402, compound

HRID 2255319Notes

Reaction equation

HRID 2255319 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH3:17][C:18]1[CH:19]=[C:20]([CH:37]=[CH:38][CH:39]=1)[CH2:21][N:22]1[C:30]2[C:25](=[CH:26][C:27](/[C:31](/[CH3:36])=[CH:32]/[C:33](O)=[O:34])=[CH:28][CH:29]=2)[CH:24]=[CH:23]1>>[CH3:17][C:18]1[CH:19]=[C:20]([CH:37]=[CH:38][CH:39]=1)[CH2:21][N:22]1[C:30]2[C:25](=[CH:26][C:27](/[C:31](/[CH3:36])=[CH:32]/[C:33]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:34])=[CH:28][CH:29]=2)[CH:24]=[CH:23]1

Participants

3

Reactant 2

HCID 10402839HCID 10402839, compoundHCID 11816929Ethyl 4-(2-aminophenoxy)butanoate

Product 1

HCID 10480402HCID 10480402, compound

Procedure

327 mg of compound 32 was obtained in a similar manner to those described in the Examples 1 and 2 using 566 mg of ethyl 4-(2-aminophenoxy)butyrate and 387 mg of 3-[1-(3-methylbenzyl)indole-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-066b73e62553405c80f4e7db5e2c5b2a
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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