HCID 9975712, compound → HCID 10459819, compound

HRID 2255321Notes

Reaction equation

HRID 2255321 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[F:17][C:18]([F:42])([F:41])[C:19]1[CH:40]=[CH:39][C:22]([CH2:23][N:24]2[C:32]3[C:27](=[CH:28][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35](O)=[O:36])=[CH:30][CH:31]=3)[CH:26]=[CH:25]2)=[CH:21][CH:20]=1>>[F:41][C:18]([F:17])([F:42])[C:19]1[CH:20]=[CH:21][C:22]([CH2:23][N:24]2[C:32]3[C:27](=[CH:28][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35]([NH:1][C:2]4[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=4[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:36])=[CH:30][CH:31]=3)[CH:26]=[CH:25]2)=[CH:39][CH:40]=1

Participants

3

Reactant 2

HCID 9975712HCID 9975712, compoundHCID 11816929Ethyl 4-(2-aminophenoxy)butanoate

Product 1

HCID 10459819HCID 10459819, compound

Procedure

267 mg of compound 34 was obtained in a similar manner to those described in the Examples 1 and 2 using 563 mg of ethyl 4-(2-aminophenoxy)butyrate and 451 mg of 3-[1-(4-trifluoromethylbenzyl)indol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-1edd3b03cd2646f18f9806d5810ac6ea
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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