HCID 10471307, compound → HCID 10051624, compound

HRID 2255322Notes

Reaction equation

HRID 2255322 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH3:17][O:18][C:19]1[CH:40]=[CH:39][C:22]([CH2:23][N:24]2[C:32]3[C:27](=[CH:28][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35](O)=[O:36])=[CH:30][CH:31]=3)[CH:26]=[CH:25]2)=[CH:21][CH:20]=1>>[CH3:17][O:18][C:19]1[CH:40]=[CH:39][C:22]([CH2:23][N:24]2[C:32]3[C:27](=[CH:28][C:29](/[C:33](/[CH3:38])=[CH:34]/[C:35]([NH:1][C:2]4[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=4[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:36])=[CH:30][CH:31]=3)[CH:26]=[CH:25]2)=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 10471307HCID 10471307, compoundHCID 11816929Ethyl 4-(2-aminophenoxy)butanoate

Product 1

HCID 10051624HCID 10051624, compound

Procedure

270 mg of compound 35 was obtained in a similar manner to those described in the Examples 1 and 2 using 615 mg of ethyl 4-(2-aminophenoxy)butyrate and 443 mg of 3-[1-(4-methoxybenzyl)indol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-ac05a633c1a84137bf56cdc83bdb61c6
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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