HCID 11725263, compound → HCID 10346732, compound

HRID 2255324Notes

Reaction equation

HRID 2255324 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[C:17]([C:21]1[CH:42]=[CH:41][C:24]([CH2:25][N:26]2[C:34]3[C:29](=[CH:30][C:31](/[C:35](/[CH3:40])=[CH:36]/[C:37](O)=[O:38])=[CH:32][CH:33]=3)[CH:28]=[CH:27]2)=[CH:23][CH:22]=1)([CH3:20])([CH3:19])[CH3:18]>>[C:17]([C:21]1[CH:42]=[CH:41][C:24]([CH2:25][N:26]2[C:34]3[C:29](=[CH:30][C:31](/[C:35](/[CH3:40])=[CH:36]/[C:37]([NH:1][C:2]4[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=4[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:38])=[CH:32][CH:33]=3)[CH:28]=[CH:27]2)=[CH:23][CH:22]=1)([CH3:20])([CH3:18])[CH3:19]

Participants

3

Reactant 2

HCID 11725263HCID 11725263, compoundHCID 11816929Ethyl 4-(2-aminophenoxy)butanoate

Product 1

HCID 10346732HCID 10346732, compound

Procedure

177 mg of compound 37 was obtained in a similar manner to those described in the Examples 1 and 2 using 513 mg of ethyl 4-(2-aminophenoxy)butyrate and 400 mg of 3-[1-(4-tert-butylbenzyl)indol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-4d1dcb3b7295481fa60dab0855ead640
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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