HCID 10380393, compound → HCID 10073984, compound

HRID 2255325Notes

Reaction equation

HRID 2255325 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH3:17][CH:18]([N:25]1[C:33]2[C:28](=[CH:29][C:30](/[C:34](/[CH3:39])=[CH:35]/[C:36](O)=[O:37])=[CH:31][CH:32]=2)[CH:27]=[CH:26]1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH3:17][CH:18]([N:25]1[C:33]2[C:28](=[CH:29][C:30](/[C:34](/[CH3:39])=[CH:35]/[C:36]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:37])=[CH:31][CH:32]=2)[CH:27]=[CH:26]1)[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 10380393HCID 10380393, compoundHCID 11816929Ethyl 4-(2-aminophenoxy)butanoate

Product 1

HCID 10073984HCID 10073984, compound

Procedure

111 mg of compound 38 was obtained in a similar manner to those described in the Examples 1 and 2 using 393 mg of ethyl 4-(2-aminophenoxy)butyrate and 268 mg of 3-[1-(α-methylbenzyl)indol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-853f85a12b5342959ce3c7df125a506c
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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