HCID 10041635, compound → HCID 10345729, compound

HRID 2255326Notes

Reaction equation

HRID 2255326 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH2:17]([CH:19]([N:26]1[C:34]2[C:29](=[CH:30][C:31](/[C:35](/[CH3:40])=[CH:36]/[C:37](O)=[O:38])=[CH:32][CH:33]=2)[CH:28]=[CH:27]1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH3:18]>>[CH2:17]([CH:19]([N:26]1[C:34]2[C:29](=[CH:30][C:31](/[C:35](/[CH3:40])=[CH:36]/[C:37]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:38])=[CH:32][CH:33]=2)[CH:28]=[CH:27]1)[C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)[CH3:18]

Participants

3

Reactant 2

HCID 10041635HCID 10041635, compoundHCID 11816929Ethyl 4-(2-aminophenoxy)butanoate

Product 1

HCID 10345729HCID 10345729, compound

Procedure

73 mg of compound 40 was obtained in a similar manner to those described in Examples 1 and 2 using 465 mg of ethyl 4-(2-aminophenoxy)butyrate and 333 mg of 3-[1-(α-ethylbenzyl)indol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-b42fcc66367344f786148476b1c551a1
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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