HCID 10404590, compound → HCID 9983825, compound

HRID 2255327Notes

Reaction equation

HRID 2255327 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH2:17]([CH:20]([N:27]1[C:35]2[C:30](=[CH:31][C:32](/[C:36](/[CH3:41])=[CH:37]/[C:38](O)=[O:39])=[CH:33][CH:34]=2)[CH:29]=[CH:28]1)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[CH2:18][CH3:19]>>[CH2:17]([CH:20]([N:27]1[C:35]2[C:30](=[CH:31][C:32](/[C:36](/[CH3:41])=[CH:37]/[C:38]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:39])=[CH:33][CH:34]=2)[CH:29]=[CH:28]1)[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)[CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 10404590HCID 10404590, compoundHCID 11816929Ethyl 4-(2-aminophenoxy)butanoate

Product 1

HCID 9983825HCID 9983825, compound

Procedure

484 mg of compound 41 was obtained in a similar manner to those described in Examples 1 and 2 using 835 mg of ethyl 4-(2-aminophenoxy)butyrate and 626 mg of 3-[1-(α-propylbenzyl)indol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-b47be8e78e0e47ac90b762102ba0d586
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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