Ethyl 4-(2-aminophenoxy)butanoate → HCID 67754257, compound

HRID 2255336Notes

Reaction equation

HRID 2255336 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[F:17][C:18]1[CH:45]=[CH:44][C:21]([CH:22]([N:29]2[C:37]3[C:32](=[CH:33][C:34](/[C:38](/[CH3:43])=[CH:39]/[C:40](O)=[O:41])=[CH:35][CH:36]=3)[CH:31]=[CH:30]2)[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[CH:20][CH:19]=1>>[F:17][C:18]1[CH:45]=[CH:44][C:21]([CH:22]([N:29]2[C:37]3[C:32](=[CH:33][C:34](/[C:38](/[CH3:43])=[CH:39]/[C:40]([NH:1][C:2]4[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=4[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:41])=[CH:35][CH:36]=3)[CH:31]=[CH:30]2)[C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=2)=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 11816929Ethyl 4-(2-aminophenoxy)butanoateHCID 67754203HCID 67754203, compound

Product 1

HCID 67754257HCID 67754257, compound

Procedure

0.6 g of compound 57 was obtained in a similar manner to those described in the Examples 1 and 2 using 0.91 g of ethyl 4-(2-aminophenoxy)butyrate and 0.79 g of 3-[1-(4-fluorobenzhydryl)indol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-2a7dd5a2634f4111885a0eec3c2d686d
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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