Ethyl 4-(2-aminophenoxy)butanoate → HCID 67754258, compound

HRID 2255337Notes

Reaction equation

HRID 2255337 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[F:17][C:18]1[CH:45]=[CH:44][CH:43]=[CH:42][C:19]=1[CH:20]([N:27]1[C:35]2[C:30](=[CH:31][C:32](/[C:36](/[CH3:41])=[CH:37]/[C:38](O)=[O:39])=[CH:33][CH:34]=2)[CH:29]=[CH:28]1)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[F:17][C:18]1[CH:45]=[CH:44][CH:43]=[CH:42][C:19]=1[CH:20]([N:27]1[C:35]2[C:30](=[CH:31][C:32](/[C:36](/[CH3:41])=[CH:37]/[C:38]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:39])=[CH:33][CH:34]=2)[CH:29]=[CH:28]1)[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 11816929Ethyl 4-(2-aminophenoxy)butanoateHCID 67753916HCID 67753916, compound

Product 1

HCID 67754258HCID 67754258, compound

Procedure

0.61 g of compound 58 was obtained in a similar manner to those described in the Examples 1 and 2 using 0.99 g of ethyl 4-(2-aminophenoxy)butyrate and 0.86 g of 3-[1-(2-fluorobenzhydryl)indol-5-yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-b582b17273bd4644b6af4d3178867800
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

Loading…