Ethyl 4-(2-aminophenoxy)butanoate → HCID 19741989, compound

HRID 2255342Notes

Reaction equation

HRID 2255342 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([O:10]CC)=[O:9].[CH3:17][C:18]1[CH:46]=[CH:45][CH:44]=[CH:43][C:19]=1[CH:20]([N:28]1[C:36]2[C:31](=[CH:32][C:33](/[C:37](/[CH3:42])=[CH:38]/[C:39](O)=[O:40])=[CH:34][CH:35]=2)[CH:30]=[CH:29]1)[C:21]1[CH:26]=[CH:25][CH:24]=[C:23]([CH3:27])[CH:22]=1>>[CH3:17][C:18]1[CH:46]=[CH:45][CH:44]=[CH:43][C:19]=1[CH:20]([N:28]1[C:36]2[C:31](=[CH:32][C:33](/[C:37](/[CH3:42])=[CH:38]/[C:39]([NH:1][C:2]3[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=3[O:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])=[O:40])=[CH:34][CH:35]=2)[CH:30]=[CH:29]1)[C:21]1[CH:26]=[CH:25][CH:24]=[C:23]([CH3:27])[CH:22]=1

Participants

3

Reactant 2

HCID 11816929Ethyl 4-(2-aminophenoxy)butanoateHCID 19742041HCID 19742041, compound

Product 1

HCID 19741989HCID 19741989, compound

Procedure

0.20 g of compound 73 was obtained in a similar manner to those described in the Examples 1 and 2 using 0.41 g of ethyl 4-(2-aminophenoxy)butyrate and 0.36 g of 3-[1-(2,3'-dimethylbenzhydryl)indol-5yl]isocrotonic acid obtained according to the procedures described in the Reference Examples 1-4.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-c9819289646842278714ba867fa84ff7
Source dataset
uspto-grants-1993_08
Patent number
US05239083

Reaction notes

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