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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225535Generated: October 27, 2026

Trifluoroacetic acid → Isoindoline-4-carbonitrile

https://huagongshe.com/reaction/225535

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant2-trityl-2,3-dihydro-1H-isoindole-4-carbonitrileHCID 57753431—
ProductIsoindoline-4-carbonitrileHCID 50999317—

Reaction Steps

Prepared in analogy to Example A2(c) from 2-trityl-2,3-dihydro-1H-isoindole-4-carbonitrile and trifluoroacetic acid. Light brown solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-a856224bfa874f9a8be8f3814497175f
Source noteuspto-grants-2009_07