HCID 4052667, compound → HCID 19738031, compound

HRID 2255384Notes

Reaction equation

HRID 2255384 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[CH:11][C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)[C:9]#[N:10])=[CH:4][CH:3]=1.[BH4-].[Na+]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]([CH2:11][C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)[C:9]#[N:10])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 4052667HCID 4052667, compoundHCID 4311764Sodium borohydride

Product 1

HCID 19738031HCID 19738031, compound

Procedure

This intermediate (64 g.) was prepared using the procedure described in Example 12b except using 80 g. (0.3 mole) of 2-(4-chlorophenyl)-3-(3-pyridyl)acrylonitrile, and 14 g. (0.36 mole) of sodium borohydride.

Workup

  1. customThis intermediate (64 g.) was prepared

Sources & evidence

ORD record
ord-5160fbaebb17448aa4fa16ce8eaf9a31
Source dataset
uspto-grants-1993_08
Patent number
US05240925

Reaction notes

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