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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225554Generated: October 28, 2026

Sodium borohydride → (2-Fluoro-6-hydroxymethyl-4-trifluoromethyl-phenyl)-methanol

https://huagongshe.com/reaction/225554

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium borohydrideHCID 4311764—
Reactant4-Fluoro-6-trifluoromethyl-3H-isobenzofuran-1-oneHCID 57753255—
Product(2-Fluoro-6-hydroxymethyl-4-trifluoromethyl-phenyl)-methanolHCID 57753663—

Reaction Steps

Prepared in analogy to Example A16(a) from 4-Fluoro-6-trifluoromethyl-3H-isobenzofuran-1-one e and sodium borohydride. Colorless oil. MS (m/e): 225.1 ([M+H+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-df8964264c0d4f8b917d453468251840
Source noteuspto-grants-2009_07