HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1-Benzyloctahydropyrrolo[3,4-b]pyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Ethyl 1-benzylhexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate | HCID 11086974 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 1-Benzyloctahydropyrrolo[3,4-b]pyrrole | HCID 22562208 | — |
Reaction Steps
55.6 g (0.2 mol) of ethyl 2-benzyl-2,7-diazabicyclo[3.3.0]octane -7-carboxylate are heated under reflux overnight with 300 ml of concentrated hydrochloric acid. The mixture is then rendered alkaline with potassium carbonate and extracted five times with 100 ml of chloroform each time, the extracts are dried over potassium carbonate and concentrated, and the residue is distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05241076 |
| Source dataset | uspto-grants-1993_08 |
| ORD ID | ord-15d9ca2630de4a709b83e203c0f1386f |
| Source note | uspto-grants-1993_08 |