Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225579Generated: October 31, 2026

Hydrochloric Acid → 5-Chloro-6-piperidin-1-yl-2,3-dihydro-1H-isoindole hydrochloride

https://huagongshe.com/reaction/225579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-Chloro-6-piperidin-1-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753525—
Product5-Chloro-6-piperidin-1-yl-2,3-dihydro-1H-isoindole hydrochlorideHCID 68824080—

Reaction Steps

Prepared in analogy to Example A3(e) from 5-chloro-6-piperidin-1-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and hydrochloric acid. Brown solid. MS (m/e): 239.2 ({37Cl}M+H+, 35%), 237.1 ({35Cl}M+H+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-da7922ba98d74a298567aed8dd93e9b6
Source noteuspto-grants-2009_07