4-Bromobenzoic acid → 4-Bromobenzoyl chloride

Participants

Reaction Steps

A mixture of 4-bromobenzoic acid (5 g) and thionyl chloride (15 mL) was stirred at the room temperature for 16 hours, heated to reflux for 6 hours and then stirred at room temperature for 16 hours. At the end of this period, the reaction mixture was diluted with chloroform and evaporated. The residue was treated with toluene, evaporated and the process was repeated three times. The product was obtained as a solid (5.63 g); MS: 221; NMR: 7,5 (m, 2), 7.9-8.1 (m, 2).

Provenance & Evidence