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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225623Generated: October 25, 2026

3-Oxa-8-azabicyclo(3.2.1)octane hydrochloride → HCID 57753423, compound

https://huagongshe.com/reaction/225623

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Oxa-8-azabicyclo(3.2.1)octane hydrochlorideHCID 53401129—
Reactanttert-Butyl 5-iodoisoindoline-2-carboxylateHCID 57753580—
ProductHCID 57753423HCID 57753423—

Reaction Steps

Prepared in analogy to Example A3(d) from 5-iodo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester (Example A38(b)) and 3-oxa-8-azabicyclo[3.2.1]octane hydrochloride. Yellow oil. MS (m/e): 331.4 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-44a0b02d814c404fb024ff380e83f53f
Source noteuspto-grants-2009_07