HCID 19029343, compound → HCID 11499576, compound

Participants

Reaction Steps

3-(3,4-Difluorophenyl)glutaric acid (7.4 g) was treated with acetyl chloride (50 mL) and the resulting mixture heated at reflux for 5 hours. The cooled reaction mixture was then azeotroped with toluene (3×100 mL) and concentrated under reduced pressure. The residue was slurried with diethyl ether and filtered to afford the title compound (6.5 g).

Provenance & Evidence