Triethylamine → HCID 19029363, compound

Participants

Reaction Steps

3,4-Dichloro-beta-(2-hydroxyethyl)-N-(4-chlorophenyl)-N-methylbenzenepropanamide (2.1 g) in CH2Cl2 (40 mL) was cooled to -5° to -10° C. and treated sequentially with Et3N (0.69 g), and methanesulfonyl chloride (0.78 g). After two hours the reaction mixture was washed with water(3×50 mL) and the organic layer separated, dried over MgSO4, filtered and concentrated under reduced pressure to give the title compound (2.3 g).

Provenance & Evidence