Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225630Generated: October 29, 2026

Trifluoroacetic acid → 5-Cyclopropyl-6-(tetrahydro-pyran-4-yl)-2,3-dihydro-1H-isoindole trifluoro-acetate

https://huagongshe.com/reaction/225630

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant5-Cyclopropyl-6-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl EsterHCID 57753305—
Product5-Cyclopropyl-6-(tetrahydro-pyran-4-yl)-2,3-dihydro-1H-isoindole trifluoro-acetateHCID 68825856—

Reaction Steps

Prepared in analogy to Example A2(c) from 5-cyclopropyl-6-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and trifluoroacetic acid. Brown solid. MS (m/e): 244.4 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-c4dc8c1525464f2ba8d29e76a02814ae
Source noteuspto-grants-2009_07