Triethylamine → HCID 57093000, compound

Participants

Reaction Steps

3,4-Dichloro-beta-(2-hydroxyethyl)-N-methyl-N-(4-methoxyphenyl)-benzene propanamide (2.0 g) in CH2Cl2 (50 mL) was cooled to -5° to -10° C. and treated sequentially with Et3N (0.911 mL), and methanesulfonyl chloride (0.64 mL). After two hours the reaction mixture was washed with water (100 mL), brine (100 mL) and the organic layer separated, dried over MgSO4, filtered and concentrated under reduced pressure to give the title compound (2.56 g).

Provenance & Evidence