HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57753365, compound → 4-(2,3-Dihydro-1H-isoindol-5-yl)-tetrahydro-pyran-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57753365 | HCID 57753365 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(2,3-Dihydro-1H-isoindol-5-yl)-tetrahydro-pyran-4-ol | HCID 57753680 | 100% |
Reaction Steps
To a stirred solution 0.39 mmol 4-(2-benzyl-2,3-dihydro-1H-isoindol-5-yl)-tetrahydro-pyran-4-ol in 20 ml methanol was added 40 mg 10% palladium on charcoal and the mixture was stirred under an atmosphere of hydrogen for 3 h. The reaction mixture was then filtered and the filtrate was concentrated in vacuo to yield the title compound as a yellow solid (100% yield). MS (m/e): 220.3 ([M+H]+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557114B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-339e995f353440878f69c6f08c4012cd |
| Source note | uspto-grants-2009_07 |