HCID 19916845, compound → HCID 54395695, compound

HRID 2256350Notes

Reaction equation

HRID 2256350 reaction equation
[N:1]1([NH:7][C:8](=[O:34])[C:9]2[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]([C:19]3[CH:28]=[CH:27][C:26]4[C:25]([CH3:30])([CH3:29])[CH2:24][CH2:23][C:22]([CH3:32])([CH3:31])[C:21]=4[CH:20]=3)=[O:18])=[CH:11][C:10]=2[OH:33])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1>C(O)C>[N:1]1([NH:7][C:8](=[O:34])[C:9]2[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH:17]([OH:18])[C:19]3[CH:28]=[CH:27][C:26]4[C:25]([CH3:30])([CH3:29])[CH2:24][CH2:23][C:22]([CH3:31])([CH3:32])[C:21]=4[CH:20]=3)=[CH:11][C:10]=2[OH:33])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1

Participants

3

Reactant 1

HCID 19916845HCID 19916845, compound

Product 1

HCID 54395695HCID 54395695, compoundYield 77%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Starting from 5.5 g (12 mmol) of N-morpholinyl-2-hydroxy-4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthoylmethoxy)benzamide in a manner analogous to Example 10 and by recrystallisation in 10 volume of ethanol, 4.24 g (77%) of the expected product of melting point 153° C. are collected.

Sources & evidence

ORD record
ord-21ab228e0f6b44a6b753f606b1a3326d
Source dataset
uspto-grants-1997_08
Patent number
US05654331

Reaction notes

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