Sodium borohydride → HCID 19029921, compound

Participants

Reaction Steps

To a solution of 3-(2-aminoethyl)-5-(4-phthalimidobutyloxy)-1H-indole hydrochloride (0.057 g, 0.14 mmol) in methanol (10 mL) was added sodium borohydride (0.057 g, 1.36 mmol) and the resulting mixture was stirred at room temperature for 4 hours. The solution was then poured onto a silica gel column and the product eluted with methanol/ammonium hydroxide (19:1) to give the title compound as a syrup (0.052 g, 100%).

Provenance & Evidence