HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-allyl-N-carbobenzyloxy-4-(4-pyridyl)-3,5-difluoraniline → (+/-)-5-Iodomethyl-3-[4-(4-pyridyl)-3,5-difluorophenyl]-2-oxazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-allyl-N-carbobenzyloxy-4-(4-pyridyl)-3,5-difluoraniline | HCID 9999803 | — |
| Reactant | Oxazolidinone iodide | HCID 21585223 | — |
| Product | (+/-)-5-Iodomethyl-3-[4-(4-pyridyl)-3,5-difluorophenyl]-2-oxazolidinone | HCID 10432033 | — |
Reaction Steps
Following the general procedure of PREPARATION 5 and making non-critical variations but starting with N-allyl-N-carbobenzyloxy-4-(4-pyridyl)-3,5-difluoraniline (PREPARATION 10, 241 mg, 0.634 mmol) is converted to the oxazolidinone iodide. The crude product is not purified further, NMR (CDCl3) δ 8.70, 7.44, 7.32, 4.85-4.73, 4.19, 3.80, 3.50, 3.40.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05654435 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-67ec3875fc4643bdb9b17a5d6e80d299 |
| Source note | uspto-grants-1997_08 |