3-(2-Benzyl-2,3-Dihydro-1H-isoindol-5-yl)-tetrahydro-furan-3-ol → 3-(2,3-Dihydro-1H-isoindol-5-yl)-tetrahydro-furan-3-ol

HRID 225641Notes

Reaction equation

HRID 225641 reaction equation
C([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([C:17]3([OH:22])[CH2:21][CH2:20][O:19][CH2:18]3)[CH:14]=2)[CH2:9]1)C1C=CC=CC=1.[H][H]>>[CH2:9]1[C:10]2[C:15](=[CH:14][C:13]([C:17]3([OH:22])[CH2:21][CH2:20][O:19][CH2:18]3)=[CH:12][CH:11]=2)[CH2:16][NH:8]1

Participants

3

Reactant 2

HCID 577533893-(2-Benzyl-2,3-Dihydro-1H-isoindol-5-yl)-tetrahydro-furan-3-olHCID 178418361HCID 178418361, compound

Product 1

HCID 577534993-(2,3-Dihydro-1H-isoindol-5-yl)-tetrahydro-furan-3-ol

Procedure

Prepared in analogy to Example A62(c) from 3-(2-benzyl-2,3-dihydro-1H-isoindol-5-yl)-tetrahydro-furan-3-ol and hydrogen. Brown oil. MS (m/e): 206.1 ([M+H]+, 100%).

Sources & evidence

ORD record
ord-1023928672a54771a838c937a7f56158
Source dataset
uspto-grants-2009_07
Patent number
US07557114B2

Reaction notes

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