HuagongsheHuagongshe Chemistry Print Report · For research reference only
Npc182939 → Succinic anhydride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Npc182939 | HCID 456410 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | Succinic anhydride | HCID 7922 | — |
| Product | Npc182939 | HCID 456410 | — |
Reaction Steps
The use of this procedure for the preparation of the dihydroartemisinin hemisuccinate, but with dihydroartemisinin, succinic anhydride and 4-(N,N-dimethylamino)pyridine in the molar ratio 1:1.5:0.20 and a reaction time of 5 hours, afforded dihydroartemisinin hemisuccinate in a yield of 65%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05654446 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-15bb11744adb49d5b174b3682d181f40 |
| Source note | uspto-grants-1997_08 |