2-Benzyl-5-(2,5-dihydro-furan-3-yl)-2,3-dihydro-1H-isoindole → 5-(Tetrahydro-furan-3-yl)-2,3-dihydro-1H-isoindole

HRID 225643Notes

Reaction equation

HRID 225643 reaction equation
C([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([C:17]3[CH2:18][O:19][CH2:20][CH:21]=3)[CH:14]=2)[CH2:9]1)C1C=CC=CC=1.[H][H]>>[O:19]1[CH2:20][CH2:21][CH:17]([C:13]2[CH:14]=[C:15]3[C:10](=[CH:11][CH:12]=2)[CH2:9][NH:8][CH2:16]3)[CH2:18]1

Participants

3

Reactant 2

HCID 577534442-Benzyl-5-(2,5-dihydro-furan-3-yl)-2,3-dihydro-1H-isoindoleHCID 178418361HCID 178418361, compound

Product 1

HCID 577535325-(Tetrahydro-furan-3-yl)-2,3-dihydro-1H-isoindole

Procedure

Prepared in analogy to Example A62(c) from 2-benzyl-5-(2,5-dihydro-furan-3-yl)-2,3-dihydro-1H-isoindole and hydrogen. Brown oil. MS (m/e): 190.4 ([M+H]+, 100%).

Sources & evidence

ORD record
ord-b9d16d3aaeb046c2ba1e55d50b8018e7
Source dataset
uspto-grants-2009_07
Patent number
US07557114B2

Reaction notes

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