Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225648Generated: October 30, 2026

Trifluoroacetic acid → 5-Ethyl-6-(tetrahydro-pyran-4-yl)-2,3-Dihydro-1H-isoindole trifluoro-acetate

https://huagongshe.com/reaction/225648

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant5-Ethyl-6-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753461—
Product5-Ethyl-6-(tetrahydro-pyran-4-yl)-2,3-Dihydro-1H-isoindole trifluoro-acetateHCID 68824165—

Reaction Steps

Prepared in analogy to Example A2(c) from 5-ethyl-6-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and trifluoroacetic acid. Yellow oil. MS (m/e): 232.1 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-aa46427ebc7a495b83dee6142df59f0c
Source noteuspto-grants-2009_07