HuagongsheHuagongshe Chemistry Print Report · For research reference only
rel-(2R,6S)-4-[2,3-Dihydro-2-(phenylmethyl)-1H-isoindol-5-yl]tetrahydro-2,6-dimethyl-2H-pyran-4-ol → (2S,6R)-4-(2,3-Dihydro-1H-isoindol-5-yl)-2,6-dimethyl-tetrahydro-pyran-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | rel-(2R,6S)-4-[2,3-Dihydro-2-(phenylmethyl)-1H-isoindol-5-yl]tetrahydro-2,6-dimethyl-2H-pyran-4-ol | HCID 57753466 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Product | (2S,6R)-4-(2,3-Dihydro-1H-isoindol-5-yl)-2,6-dimethyl-tetrahydro-pyran-4-ol | HCID 57753310 | — |
Reaction Steps
Prepared in analogy to Example A62(c) from (2S,6R)-4-(2-benzyl-2,3-dihydro-1H-isoindol-5-yl)-2,6-dimethyl-tetrahydro-pyran-4-ol and hydrogen. Brown oil. MS (m/e): 248.3 ([M+H]+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557114B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-ea0e9923eca147f1b16fa884529576bb |
| Source note | uspto-grants-2009_07 |