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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225657Generated: October 29, 2026

Hydrochloric Acid → Rac-5-(tetrahydro-pyran-3-yl)-2,3-dihydro-1h-isoindole

https://huagongshe.com/reaction/225657

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantRac-5-(tetrahydro-pyran-3-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753408—
ProductRac-5-(tetrahydro-pyran-3-yl)-2,3-dihydro-1h-isoindoleHCID 57753682—

Reaction Steps

Prepared in analogy to Example A3(e) from rac-5-(tetrahydro-pyran-3-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and hydrochloric acid. Brown oil. MS (m/e): 204.3 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-1c5dbe398917480998b965a2a73a1307
Source noteuspto-grants-2009_07