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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225659Generated: October 31, 2026

Trifluoroacetic acid → 5-(2,2,2-Trifluoro-ethoxy)-2,3-dihydro-1H-isoindole trifluoroacetate

https://huagongshe.com/reaction/225659

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant5-(2,2,2-Trifluoro-ethoxy)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753712—
Product5-(2,2,2-Trifluoro-ethoxy)-2,3-dihydro-1H-isoindole trifluoroacetateHCID 86607009—

Reaction Steps

Prepared in analogy to Example A2(c) from 5-(2,2,2-trifluoro-ethoxy)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and trifluoroacetic acid. Brown oil. MS (m/e): 218.4 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-dfb471b8c1e446cf858288ef2a2c761e
Source noteuspto-grants-2009_07